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KMID : 0360220080490010098
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Journal of the Korean Ophthalmological Society
2008 Volume.49 No. 1 p.98 ~ p.103
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Factors Mediating Effects on the Retinal Nerve Fiber Layer Thickness in Normal Children
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Cho Yun-Keun
Lee Young-Chun
Lee Se-Yup
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Abstract
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Purpose : The peripapillary retinal nerve fiber layer thickness (RNFL) was measured in normal children using
optical coherence tomography (OCT), and the effect of various factors on the RNFL thickness was examined.
Methods : From April 2006 to January 2007, the RNFL thickness of 74 normal children (148 eyes) between
the ages of 4 and 17 years old was measured by OCT, and the effect of factors such as age, gender, refractive
error, C/D ratios, cooperation, and laterality on the peripapillary RNFL thickness was analyzed.
Results : The mean age of the patients was 10.2 years (4~17 years), and the mean peripapillary RNFL
thickness was 106.3±12.8 μm. As to the thickness of the different peripapillary locations, the superior side
was thickest (135.3±20.6 μm), followed in order by the inferior side (130.9±23.0 μm), the temporal side
(86.3±18.9 μm), and the nasal side (71.9±20.8 μm). The refractive error was correlated positively with
RNFL thickness (r=0.277, p=0.001), and age correlated negatively with RNFL thickness (r=-0.194, p=0.018).
Conclusion : RNFL thickness in normal children increases as the refractive error becomes hyperopic and
decreases with age. The data about RNFL thickness of normal children obtained in this study may provide
useful information for an early diagnosis of pediatric neuroophthalmologic disease and for monitoring its
progression.
J Korean Ophthalmol Soc 49(1):98-103, 2008
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KEYWORD
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Normal children, Optical coherence tomography, Retinal nerve fiber Layer thickness
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